中性粒细胞在COVID-19发生发展中作用的研究进展

doi:10.16352/j.issn.1001-6325.2023.02.341

摘要/Abstract

摘要： 中性粒细胞是COVID-19感染中出现较多的固有免疫细胞。中性粒细胞数量以及血浆中性粒细胞胞外诱捕网(NETs)水平与COVID-19严重程度呈正相关。本文综述中性粒细胞以及NETs的生成与降解参与COVID-19的病理过程,以期对深入研究COVID-19的发病机制以及疾病干预提供借鉴。

关键词: COVID-19, SARS-CoV-2, 中性粒细胞, 中性粒细胞胞外诱捕网

Abstract: Neutrophils are more innate immune cells found in coronavirus disease in 2019(COVID-19). The accounting of neutrophils and the level of plasma neutrophil extracellular traps(NETs) were positively correlated with the severity of COVID-19. This article reviews the relevant studies of neutrophils, formation and degradation of NETs involved in the pathological process of COVID-19, providing the reference for further studies of pathogenesis and intervention.

Key words: COVID-19, SARS-CoV-2, neutrophil, neutrophil extracellular traps

中图分类号:

R512.99

王亮, 司萍, 沈永明, 崔晓鸣. 中性粒细胞在COVID-19发生发展中作用的研究进展[J]. 基础医学与临床, 2023, 43(2): 341-345.

WANG Liang, SI Ping, SHEN Yongming, CUI Xiaoming. Role of neutrophils in the development and progression of COVID-19[J]. Basic & Clinical Medicine, 2023, 43(2): 341-345.

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