基础医学与临床 ›› 2020, Vol. 40 ›› Issue (12): 1691-1694.

• 临床研究 • 上一篇    下一篇

Halcyon医用电子直线加速器对142例肺癌患者常规分割治疗模式下靶区外放边界的分析

徐浩然, 孙显松, 王欣海, 胡克, 邱杰*, 张福泉   

  1. 中国医学科学院 北京协和医学院 北京协和医院 放射治疗科,北京 100730
  • 收稿日期:2020-09-16 修回日期:2020-10-23 出版日期:2020-12-05 发布日期:2020-11-30
  • 通讯作者: * 13501015586@139.com
  • 基金资助:
    科技部国家重点研发计划(2016YFC0105206)

Halcyon analyzed target margin in 142 patients with lung cancer treated by conventional segmentation therapy

XU Hao-ran, SUN Xian-song, WANG Xin-hai, HU Ke, QIU Jie*, ZHANG Fu-quan   

  1. Department of Radiotherapy, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730,China
  • Received:2020-09-16 Revised:2020-10-23 Online:2020-12-05 Published:2020-11-30
  • Contact: * 13501015586@139.com

摘要: 目的 应用Halcyon医用电子直线加速器对肺癌常规分割摆位误差及靶区外放边界进行分析,以提高肺癌患者在Halcyon医用电子直线加速器放射治疗精度,提高疗效。方法 选取北京协和医院放疗科2019年5月至2020年8月142例肺癌患者为研究对象,采集患者整个疗程3 192组配准图像进行数据分析,计算升降方向(VRT)、进出方向(LNG)、左右方向(LAT)3个方向的误差。应用靶区外放边界公式=2.5∑+0.7δ计算,并结合ICRU50号和ICRU62号报告分析得出结果。结果 通过SPSS 21.0统计学分析得出3个方向的摆位误差分别为:VRT(0.07±1.59)mm,LNG(-0.15±4.40)mm,LAT(0.08±3.50)mm;结合ICRU50号和ICRU62号报告分析,靶区外放边界为VRT=3.69 mm,LNG=6.60 mm,LAT=5.04 mm。结论 常规分割治疗模式下,肺癌患者在Halcyon医用电子直线加速器靶区外放边界为VRT=3.69 mm,LNG=6.60 mm,LAT=5.04 mm,为临床靶区外放提供了依据。

关键词: 肺癌常规分割, Halcyon, CBCT, 摆位误差, 靶区外放边界

Abstract: Objective To analyze the conventional segmental positioning error of lung cancer with Halcyon and the outspread boundary of the target area, so as to improve the precision and efficacy of radiotherapy in patients with lung cancer with Halcyon. Methods Totally 142 patients from May 2019 to August 2020 in the radiotherapy department of Peking Union Medical College Hospital were selected in this study and 3 192 registration images were collected for data analysis of the whole course of treatment, and the errors of elevation direction (VRT), inlet and outlet direction (LNG) and left-right direction (LAT) were calculated. The outer boundary formula of target area=2.5∑+0.7 and combined with the ICRU50 and ICRU62 report analysis results. Results By SPSS 21.0 statistical analysis, the positioning errors of the three directions were as follows: VRT(0.07±1.59)mm, LNG(-0.15±4.40)mm, and LAT (0.08±3.50)mm. According to the analysis of ICRU50 and ICRU62 reports, the target margin is VRT=3.69 mm,LNG=6.60 mm and LAT=5.04 mm. Conclusions With conventional segmental treatment model, the boundary of the exotherm of the lung cancer patients in the target area of the Halcyon medical electron linac was VRT=3.69 mm, LNG=6.60 mm and LAT=5.04 mm, which provided the basis for the exotherm of the clinical target margin.

Key words: conventional segmentation of lung cancer, Halcyon, CBCT, positioning error, target margin

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