肠平滑肌细胞在肠道炎性疾病中作用的研究进展

基础医学与临床 ›› 2019, Vol. 39 ›› Issue (3): 419-422.

肠平滑肌细胞在肠道炎性疾病中作用的研究进展

李赟¹,尹跃霏¹,陈亚丽¹,张德奎²

1. 甘肃省兰州市兰大二院
2. 兰州大学第二医院

收稿日期:2018-08-28 修回日期:2018-12-24 出版日期:2019-03-05 发布日期:2019-03-05
通讯作者: 李赟 E-mail:929220250@qq.com
基金资助:
肠神经胶质细胞GDNF-GFRa1/RET自分泌环路在溃疡性结肠炎中的作用及机制;肠神经胶质细胞对肠平滑肌细胞的影响及其在炎症性肠病发病中的作用

Progress on the role of intestinal smooth muscle cells in gut inflammatory diseases

Received:2018-08-28 Revised:2018-12-24 Online:2019-03-05 Published:2019-03-05
Contact: LI YUN E-mail:929220250@qq.com
Supported by:
the role of GDNF-GFRa1/RET autocrine loop of enteric glial cell in ulcerative colitis and its mechanism;Effects of enteric glial cell on intestinal smooth muscle cell and its role in the pathogenesis of inflammatory bowel disease

摘要/Abstract

摘要： 肠平滑肌细胞（ISMC）作为胃肠道主要成员之一，在肠管蠕动、结肠运输、肠道内环境稳态等方面发挥重要作用，其结构及功能改变参与肠道炎性疾病发病过程。肠道炎性疾病常伴肠功能亢进、肠腔狭窄等症状。明确ISMC在肠道炎性疾病中的作用将为其临床治疗提供新思路。

关键词: 肠平滑肌细胞, 肠道炎性反应

Abstract: Intestinal smooth muscle cells (ISMC), as an important part of the gastrointestinal tract, play an important role in intestinal peristalsis, colonic transport, and intestinal homeostasis. Structural and functional changes of ISMC are involved in the pathogenesis of intestinal inflammatory diseases, which always accompanied by symptoms such as intestinal hyperfunction and intestinal stenosis. It can provide a hypothesis about intestinal inflammatory diseases clinical treatment to illustrate the role of ISMC in intestinal inflammatory diseases.

Key words: intestinal smooth muscle cells , Intestinal inflammation

中图分类号:

R445.9

李赟尹跃霏陈亚丽张德奎. 肠平滑肌细胞在肠道炎性疾病中作用的研究进展[J]. 基础医学与临床, 2019, 39(3): 419-422.