基础医学与临床 ›› 2017, Vol. 37 ›› Issue (9): 1308-1312.

• 临床研究 • 上一篇    下一篇

2型自身免疫性胰腺炎的临床特点

赖雅敏1,朱亮2,常晓燕3,杨红(协和)4,吕红5,杨爱明4,钱家鸣4   

  1. 1. 北京协和医院
    2. 北京协和医院放射科
    3. 中国医学科学院北京协和医学院北京协和医院
    4. 北京协和医院消化内科
    5. 北京协和医院消化内科 北京
  • 收稿日期:2017-05-18 修回日期:2017-06-24 出版日期:2017-09-05 发布日期:2017-08-28
  • 通讯作者: 钱家鸣 E-mail:qianjiaming1957@126.com

Clinical charactors of type 2 autoimmune pancreatitis

  • Received:2017-05-18 Revised:2017-06-24 Online:2017-09-05 Published:2017-08-28

摘要: 目的1型自身免疫性胰腺炎(AIP)近年来逐渐为临床所关注,然而2型AIP在亚洲人群中较为罕见。本文对北京协和医院的2型AIP患者的临床特点及诊治经验进行了总结。方法该中心所有2001年1月至2016年12月间符合国际共识诊断标准的2型AIP住院患者被纳入研究。所有入选患者的临床数据、实验室结果和影像学特征均得到详细记录、核实、统计学计算和随诊。结果共有6例2型AIP患者被纳入研究。男女比例为2/1,发病平均年龄为38.4岁。67.7%(4/6)的患者合并溃疡性结肠炎。37.7%(2/6)的患者是无症状查体发现。3例患者通过病理确诊。50%(3/6)患者影像学表现为胰腺弥漫增大,50%(3/6)患者表现为胰腺肿物。结论中国的2型AIP患者临床表现与国外报道基本一致。

关键词: 关, 慢性胰腺炎,自身免疫性胰腺炎,2型自身免疫性胰腺炎,临床特点,病理,影像学

Abstract: Objective The type 1 autoimmune pancreatitis is gradually being recognized, but the type 2 AIP is still very rare in Asia. This paper summarizes the clinical characters of type-2 AIP patients in Peking union medical college hospital(PUMCH).Methods From January 2001 to December 2016,all type 2 AIP hospitalized patients who met the ICDC were included in the study. The clinical data, laboratory results and imaging features of all patients were recorded, verified and follow-up. Results Six patients with type 2 AIP were included in the study. The ratio of men and women was 2/1, with an average age of 38.4 years. 67.7% (4/6) patients have UC. 37.7% (2/6) of patients were asymptomatic. Three patients were diagnosed by pathology. 50% (3/6) of patients showed mass of pancreas, and 50% (3/6) of patients showed pancreatic enlargement. Conclusions The clinical manifestations of the type 2 AIP patients in PUMCH are the same as those in foreign countries.

Key words: Key, Autoimmune pancreatitis, chronic pancreatitis, type 2 autoimmune pancreatitis , type 1 autoimmune pancreatitis, swollen of pancreas, pancreatic duct stricture, pancreas placeholder, pancreatitis