基础医学与临床 ›› 2015, Vol. 35 ›› Issue (8): 1042-1048.

• 研究论文 • 上一篇    下一篇

贵州省龙里县成年布依族和汉族血脂异常分析

平波1,王斌2,余杨文3,董芬2,谢勋祥1,潘利2,王棵2,毛兴华1,王谊勋1,杜月清1,许可4,庞兴龙4,陈婷4,潘慧4,马瑾4,钟勇4,王定明3,单广良2   

  1. 1. 贵州省龙里县疾病预防控制中心
    2. 中国医学科学院基础医学研究所
    3. 贵州省疾病预防控制中心
    4. 北京协和医院
  • 收稿日期:2015-04-16 修回日期:2015-06-19 出版日期:2015-08-05 发布日期:2015-07-15
  • 通讯作者: 单广良 E-mail:Guangliang-shan@hotmali.com
  • 基金资助:
    国家科技支撑计划课题

Dyslipidemia in Buyi and Han population in Longli County Guizhou province

  • Received:2015-04-16 Revised:2015-06-19 Online:2015-08-05 Published:2015-07-15

摘要: 目的 了解贵州省龙里县布依族、汉族居民血脂特征,为制定其防治措施提供依据。方法 采取多阶段抽样方法抽取县城龙山镇2个居委会、4个乡镇、4个行政村20~80岁身体健康的布依族、汉族2929名常住村民为调查对象,进行问卷调查和体格检查,并检测其血浆总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)及低密度脂蛋白胆固醇(LDL-C)。并按判断标准对血脂异常及肥胖状况进行分析。结果 布依族、汉族居民血脂异常总患病率为25.9%,男性(31.1%)显著高于女性(22.0%)(P<0.001),汉族患病率(34.0%)显著高于布依族(21.7%)(P<0.001);高TG血症患病率为16.4%,汉族(22.6%)显著高于布依族(13.2%)(P<0.001);高TC血症患病率为10.70%,布依族为9.8%,汉族为12.5%,汉族高于布依族(P<0.05);HDL-C血症患病率为5.8%,汉族(9.1%)显著高于布依族(4.2%)(P<0.001);LDL-C血症患病率为4.8%,汉族(6.0%)显著高于布依族(4.1%)(P<0.05);45~59岁年龄段、肥胖、高血压是血脂异常的主要危险因素。结论。龙里县布依族和汉族成人血脂异常以高TG、高TC血症为主。布依族和汉族高TG血症、高TC血症和高LDL-C血症患病率均高于2010年中国调查结果,血脂异常总患病率呈明显上升趋势。应重视45岁以上中年人群血脂异常的防治。

关键词: 汉族, 布依族, 血脂异常

Abstract: Objective To know characteristics of dyslipidemia in Buyi and Han residents in Longli County and to provide evidence for prevention strategies. Methods Stratified sampling was adopted to select 2 communities within the county seat of Longshan and 4 villages from 4 towns. 2929 healthy Buyi and Han residents aged between 20 to 80 years participated in this study. Their serum total cholesterol (TC), triglyceride (TG), high-density lipid-cholesterol (HDL-C), and low-density lipid cholesterol (LDL-C) were tested. Results The prevalence of dyslipidemia was 25.9% (31.1% for men, 22.0% for women, respectively). It was higher in men than in women (P<0.001). Compared with Buyi people, the prevalence was significantly higher in Han people (34.0%) then in Buyi was only 21.73% (P<0.001). The prevalence of high TG level was significantly higher in Han population (P<0.001), 13.2% in Buyi population and 22.6% in Han population, with 16.4% in the pooled sample. The prevalence of high TC level was significantly higher in Han population (P<0.05), 9.8% in Buyi population and 12.5% in Han population, with 10.7% in the pooled sample. The prevalence of low HDL-C level was significantly higher in Han population (P<0.001), 4.2% in Buyi population and 9.1% in Han population, with 5.8% in the pooled sample. The prevalence of high LDL-C level was significantly higher in Han population (P<0.05), 4.1% in Buyi population and 6.0% in Han population, with 4.8% in the pooled sample. Additionally, obesity and hypertension were the main risk factors for dyslipidemia among adults aged between 45 and 59 years. Conclusions High TG and hypercholesterolemia were the main components of dyslipidemia in Buyi and Han adults in Longli County. The prevalences of high TG, high TC, and high LDL-C were all higher than the results of 2010 national survey. Obviously, the prevalence of dyslipidemia was increasing over time. It suggested that attention should be paid for prevention and treatment of dyslipidemia in adults aged between 45 and 59 years.

Key words: Key word Han population, Buyi population, Dyslipidemia