基础医学与临床 ›› 2024, Vol. 44 ›› Issue (7): 916-920.doi: 10.16352/j.issn.1001-6325.2024.07.0916

• 特邀专题:静脉血栓栓塞症 • 上一篇    下一篇

老年患者静脉血栓栓塞症的预防

丁梦希1, 王春梅2*   

  1. 首都医科大学宣武医院 1.全科医学科;
    2.重症医学科,北京 100053
  • 收稿日期:2024-04-22 修回日期:2024-05-21 出版日期:2024-07-05 发布日期:2024-06-26
  • 通讯作者: *wangchunmei@xwhosp.org
  • 基金资助:
    首都卫生发展科研专项(首发2022-2-2016)

Prevention of venous thromboembolism in elderly patients

DING Mengxi1, WANG Chunmei2*   

  1. 1. Department of General Medicine;
    2. Department of Intensive Care Medicine, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
  • Received:2024-04-22 Revised:2024-05-21 Online:2024-07-05 Published:2024-06-26
  • Contact: *wangchunmei@xwhosp.org

摘要: 静脉血栓栓塞症(venous thromboembolism,VTE)是常见病,发病率和病死率高。在老年患者VTE发病率更高、病死率更高,年龄增加导致血栓标志物D-二聚体数值也增加,应用D-二聚体数值筛查VTE需要调整诊断阈值,年龄增加也是抗凝预防后出血的高危因素;另外,老年患者抗凝预防后仍有VTE发生;老年患者抗凝预防VTE是否需要监测,年龄与VTE复发关系尚无定论,深入研究老年预防VTE,并探索创新的VTE预防策略,是未来研究工作的方向。

关键词: 老年患者, 静脉血栓栓塞症, 预防

Abstract: Venous thromboembolism (VTE) is a common disease with high morbidity and mortality. The incidence and mortality of VTE are higher in elderly patients and increased level of D-dimer, a thrombosis marker is positively related with age. Therefore, the diagnostic threshold needs to be adjusted to screen VTE with D-dimer level. Elderly patients may still have VTE after implementation of anticoagulant prevention, and increasing age is a high risk factor for bleeding after anticoagulant prevention. Whether elderly patients need to be monitored for anticoagulant prevention of VTE, and the relationship between age and VTE recurrence remains to be determined. In-depth research on the prevention of VTE in elderly patients and exploration of innovative VTE prevention strategies may orient future research.

Key words: elderly patient, venous thromboembolism, prevention

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