基础医学与临床 ›› 2024, Vol. 44 ›› Issue (11): 1569-1572.doi: 10.16352/j.issn.1001-6325.2024.11.1569

• 临床研究 • 上一篇    下一篇

心电图P波特征与急性心肌梗死患者新发房颤相关

杨多军, 刘静涵*   

  1. 甘肃省武威肿瘤医院 心脑功能室,甘肃 武威 733000
  • 收稿日期:2024-01-15 修回日期:2024-07-12 出版日期:2024-11-05 发布日期:2024-10-31
  • 通讯作者: *18572311211@163.com
  • 基金资助:
    甘肃省武威市科技局科技计划基金(WW2101117)

Electrocardiogram P-wave sign is related to new-onset atrial fibrillation of patients with acute myocardial infarction

YANG Duojun, LIU Jinghan*   

  1. Department of Cardio-Brain Function, Wuwei Cancer Hospital of Gansu Province, Wuwei 733000, China
  • Received:2024-01-15 Revised:2024-07-12 Online:2024-11-05 Published:2024-10-31
  • Contact: *18572311211@163.com

摘要: 目的 探讨动态心电图P波特征与急性心肌梗死(AMI)患者新发房颤(NOAF)(AMI-NOAF)的关系。方法 选取甘肃省武威肿瘤医院收治的240例AMI患者,均进行动态心电图检查,收集患者动态心电图P波特征参数及临床资料,分析P波特征与AMI患者临床参数的关系。根据是否发生NOAF分为NOAF组和未发生(non-NOAF)组,采用多因素Logistic回归模型分析AMI发生NOAF的影响因素。结果 Killip Ⅲ~Ⅳ级最小P波时限(Pmin)水平低于Ⅰ~Ⅱ级,最大P波时限(Pmax)、P波离散度(Pd)水平高于Ⅰ~Ⅱ级(P<0.05);240例AMI患者中47例发生NOAF,发生率为19.58%;NOAF组Pmin水平低于未发生组,Pmax、Pd水平高于未发生组(P<0.05);NOAF组入院时心率及Killip Ⅲ~Ⅳ级占比高于未发生组(P<0.05);多因素Logistic回归分析结果显示,Killip Ⅲ~Ⅳ级、Pmax、Pd高水平是影响AMI发生NOAF的独立危险因素(P<0.05)。结论 Pmin、Pmax、Pd水平与AMI患者Killip分级有关;AMI-NOAF患者动态心电图P波特征异常,其中高水平Pmax、Pd是影响AMI发生NOAF发生的独立危险因素。

关键词: 急性心肌梗死, 心房颤动, 动态心电图, P波特征, 传导阻滞

Abstract: Objective To investigate the relationship between dynamic electrocardiogram P-wave sign and new-onset atrial fibrillation (NOAF) in patients with acute myocardial infarction (AMI)(AMI-NOAF). Methods Totally 240 patients with AMI admitted to Wuwei Cancer Hospital were examined by dynamic electrocardiogram. P-wave sign parameters and clinical data of holter electrocardiogram were collected. The relationship between P-wave sign and clinical parameters of AMI patients was analyzed. The patients were divided into NOAF group and nonoccurrence(non-NOAF) group and multivariate Logistic regression model was used to identify the influencing factors of NOAF occurrence in AMI. Results Killip Ⅲ-Ⅳ grade minimum P wave duration (Pmin) level was shorter than that of Ⅰ-Ⅱ grade. Maximum P wave duration (Pmax) and P wave dispersion (Pd) level were higher than that of Ⅰ-Ⅱ grade(P<0.05). NOAF occurred in 47 of 240 AMI patients (19.58%). The level of Pmin in NOAF group was lower than that in non-NOAF group, and the level of Pmax and Pd in NOAF group was higher than that in non-NOAF group(P<0.05). The heart rate and the proportion of Killip grade Ⅲ-Ⅳ in NOAF group were higher than those in non-NOAF group(P<0.05). Multivariate Logistic regression analysis showed that Killip Ⅲ-Ⅳgrade, high level of Pmax and Pd were independent risk factors for NOAF in AMI (P<0.05). Conclusions The level of Pmin, Pmax and Pd are correlated with Killip grading in AMI patients. AMI-NOAF patients have abnormal P-wave sign in holter electrocardiogram. The high levels of Pmax and Pd are independent risk factors of AMI and NOAF.

Key words: acute myocardial infarction, atrial fibrillation, dynamic electrocardiogram, P-wave sign, conduction block

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