基础医学与临床 ›› 2016, Vol. 36 ›› Issue (12): 1738-1742.

• 短篇综述 • 上一篇    下一篇

乳腺癌相关长链非编码RNA的研究进展

汤鸿超1,孟旭莉2   

  1. 1. 浙江中医药大学
    2. 浙江省立同德医院
  • 收稿日期:2016-02-19 修回日期:2016-04-28 出版日期:2016-12-05 发布日期:2016-11-29
  • 通讯作者: 孟旭莉 E-mail:mxlmail@126.com
  • 基金资助:
    浙江省自然科学基金;浙江省科技计划重大项目

Research progress of breast cancer related Long non-coding RNAs

Hong-Chao TANG1,   

  • Received:2016-02-19 Revised:2016-04-28 Online:2016-12-05 Published:2016-11-29

摘要: 乳腺癌在女性恶性肿瘤的发病率中高居第一,长链非编码RNA(long non-coding RNA, lncRNA)和乳腺癌的发生发展、转移和预后相关。lncRNAs可与miRNA、mRNA或蛋白相互作用以调节相关基因的表达能力,从而影响乳腺癌的治疗效果及预后情况。

关键词: 乳腺癌, 长链非编码RNA

Abstract: The breast cancer’s incidence is higher than any other malignant tumors in women. In recent studies, lncRNAs play a role in breast cancer’s development, metastasis and prognosis. LncRNAs could make a significant sense to breast cancer’s therapeutic effect and prognosis by interacting with miRNA, mRNA or protein to regulating gene expression.

Key words: breast cancer, lncRNA

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