基础医学与临床 ›› 2009, Vol. 29 ›› Issue (5): 484-487.

• 研究论文 • 上一篇    下一篇

广西壮族体循环血管阻力异常人群的分布及心脏功能分析

曹婧文 齐保申 周晓梅 韩少梅 李辉 朱广瑾   

  1. 中国医学科学院 基础医学研究所,北京协和医学院 基础学院 中国医学科学院 基础医学研究所,北京协和医学院 基础学院 中国医学科学院 基础医学研究所,北京协和医学院 基础学院 中国医学科学院 基础医学研究所,北京协和医学院 基础学院 中国医学科学院 基础医学研究所,北京协和医学院 基础学院
  • 收稿日期:2008-12-16 修回日期:2009-02-12 出版日期:2009-05-25 发布日期:2009-05-25
  • 通讯作者: 朱广瑾

Distribution of unnormal circulation vascular resistance and analysis of cardiac function in Guangxi

Jing-wen CAO, Bao-shen QI, Xiao-mei ZHOU, Shao-mei HAN, Hui LI, Guang-jin ZHU   

  1. IBMS, CAMS, School of Basic Medicine of PUMC IBMS, CAMS, School of Basic Medicine of PUMC IBMS, CAMS, School of Basic Medicine of PUMC IBMS, CAMS, School of Basic Medicine of PUMC IBMS, CAMS, School of Basic Medicine of PUMC
  • Received:2008-12-16 Revised:2009-02-12 Online:2009-05-25 Published:2009-05-25
  • Contact: Guang-jin ZHU

摘要: 目的 分析体循环血管阻力(SVR)异常在健康人群中的分布特点及心脏功能参数的相关变化。方法 用Bioz.com数字化无创血液动力学监护仪,观察919名健康人体循环血管阻力及平均动脉压(MAP)、心输出量(CO)、心脏指数(CI)、搏出量(SV)、搏出指数(SI)、左心做功量(LCW)等心功能参数。结果 体循环血管阻力异常在低年龄段和高年龄段发生率均较高;女性显著高于男性(P <0.001)。相关因素分析显示,体循环血管阻力与平均动脉压(MAP)、脉压(PP)和左心射血时间(LVET)呈正相关;而与心输出量、心脏指数、搏出量、搏出指数、左心做功量及动脉顺应性(AC)呈负相关。结论 广西壮族人群体循环血管阻力异常与年龄、性别及血压水平密切相关,体循环血管阻力升高,心输出量和心指数降低,心脏泵功能减弱。

关键词: 体循环血管阻力, 人群分布, 心脏功能

Abstract: Objective To analyze the distribution features of systemic vascular resistance(SVR)disorder in healthy subjects in Guangxi province.Methods SVR and systolic blood pressure(SBP),diastolic blood pressure(DBP),mean arterial pressure(MAP),pulse pressure(PP), cardiac output(CO),cardiac index(CI),stroke volume(SV),stroke index(SI),left ventricular ejection time (LVET),left cardiac work (LCW) and cardiovascular function were determined with Bioz.com Cardio Dynamics. Results The incidence of SVR disorder in youngster and elder was higher than other subjects .The prevalence of SVR disorders was higher among females than among males(P <0.001).SVR was positively correlated with SBP,DBP,MAP,PP,LVET,body mass index(BMI),HR was inversely associated with CO,CI,SV,SI,LCW,and arterial compliance(AC).CO and MAP were independent influencing factors with SVR.Conclusion SVR disorder is associated with age,sex,and blood pressure in populations in Guangxi province and may be a marker of vascular injury.

Key words: systemic vascular resistance, population distribution, Cardiac function