中国人弥漫性泛细支气管炎和冷凝集试验的探讨

基础医学与临床 ›› 2009, Vol. 29 ›› Issue (10): 1075-1078.

中国人弥漫性泛细支气管炎和冷凝集试验的探讨

王岚蔡柏蔷

中国医学科学院北京协和医院呼吸科中国医学科学院北京协和医院呼吸科

收稿日期:2008-12-22 修回日期:2009-02-16 出版日期:2009-10-20 发布日期:2009-10-20
通讯作者: 蔡柏蔷

Correlation between cold hemoagglutinin and diffuse panbronchiolitis in Chinese patients

Lan WANG, Bai-qiang CAI

Department of Respiratory Medicine, PUMC Hospital, CAMS Department of Respiratory Medicine, PUMC Hospital, CAMS

Received:2008-12-22 Revised:2009-02-16 Online:2009-10-20 Published:2009-10-20
Contact: Bai-qiang CAI

摘要/Abstract

摘要： 目的探讨冷凝集试验（CHA）在中国人弥漫性泛细支气管炎（DPB）的价值，为临床诊断提供线索。方法 1996 年12 月～2008 年7月在北京协和医院诊断为DPB的患者18例和国内自1996年首例DPB报道以来以病例报告形式报道的病例60例，对其进行临床、CHA试验综合分析。结果北京协和医院诊断为DPB的18例患者仅有1例CHA阳性。国内60例DPB病例，48例患者描述了CHA结果，总阳性率54.1%。CHA阳性率和治疗药物的应用、人群等有一定相关性。结论 CHA试验在中国DPB患者中的低阳性率，提示这一指标可能不适合于中国DPB的诊断标准。

关键词: 弥漫性泛细支气管炎, 冷凝集试验

Abstract: Objective To anaylaze the correlation between cold hemoagglutinin(CHA) and diffuse panbronchiolitis(DPB) in Chinese patients. Methods 18 patients diagnosed as DPB from December 1996 to July 2008 in Peking Union Medical College and 60 cases of DPB reported in mainland China from 1996 to 2008 were enrolled in the study. Result Of 18 patients diagnosed DPB in Peking Union Medical College, Only 1 patient had titer of CHA≥1:64. Of 60 cases in mainland China, 48 cases had CHA result. CHA was positive in 54.1% all cases.There may be some correlation between positive-Frequency of CHA and treatment、population et al. Conclusions Low positive-frequency of CHA in Chinese subjects, which is different from Japanese DPB patients, suggests that CHA may not be applicable to the clinical diagnostic criteria for Chinese patients.

Key words: Diffuse panbronchiolitis, Cold hemoagglutinin

王岚蔡柏蔷. 中国人弥漫性泛细支气管炎和冷凝集试验的探讨[J]. 基础医学与临床, 2009, 29(10): 1075-1078.

Lan WANG; Bai-qiang CAI. Correlation between cold hemoagglutinin and diffuse panbronchiolitis in Chinese patients[J]. Basic & Clinical Medicine, 2009, 29(10): 1075-1078.