Abstract: Pancreatic cancer is one of the most malignant cancer of all neoplasm. 85% cases are not suitable for surgery when first diagnosed. And the effects of chemotherapy and radiotherapy are not satisfactory. Therefore, molecule-targeted therapy becomes a focus in the research of pancreatic cancer recently. EGFR and VGFR inhibition therapy is the emphasis of this field, and show a great prospect in pre-clinical research. And this article reviews progress in the research of molecule-targeted therapy.

Key words: Progress in the research of molecule-targeted therapy for pancreatic cancer