Abstract: To evaluate the clinical characteristics, diagnosis and treatment procedures for adrenal pheochromocytoma and adrenal ganglioneucoma.. Methods: 32 cases of adrenal pheochromocytoma and 14 cases of adrenal ganglioneucoma surgical treated between 1999-2005 are analysed, The mean age of ganglioneucoma was 39 years old (16~63). tumor size ranged from 2.5cmcm to 15cm. The mean age of pheochromocytoma was 42 years old (19~74), tumor size ranged from 2cm to 16cm. Tumor locations in the adrenal area. All cases accept surgical operation and are confirmed by pathology. Results: Most cases of adrenal ganglioneucoma do not have any symptom but are founded incidentally. Differential are obviously between ganglioneucoma and pheochromocytoma. Conclusions: Both of adrenal ganglioneucoma and pheochromocytoma are rare diseases .CT 、urinary CA and 131I－MIBG are good methods for diagnosis .The final diagnosis depend on pathology, surgical resection of tumor is the preferred choice.