Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (8): 1302-1305.doi: 10.16352/j.issn.1001-6325.2022.08.1302

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Research progress of insulin resistance markers in atherogenesis

ZHAO Mao-yu1, LI You-mei1, LIU Huan-yun2, MAO Qi1*   

  1. 1. Department of Cardiology, the Second Affiliated Hospital of Army Medical University,Chongqing 400037;
    2. Department of Cardiology, the First People's Hospital of Chongqing Liangjiang New Area, Chongqing 401121, China
  • Received:2021-04-15 Revised:2021-08-13 Online:2022-08-05 Published:2022-08-01
  • Contact: *

Abstract: Insulin resistance (IR) is the pivotal link between metabolic disorders and atherosclerosis (AS). Insulin resistance plays an important role in the initiation and progression of atherosclerosis, and its underlying mechanism involves complex pathophysiological processes including endothelial injury, inflammatory reaction, and oxidative stress. Insulin resistance markers presented the potential association of metabolic risk with atherosclerosis and the detection of insulin resistance markers may support strategy development for the clinical management of cardiovascular diseases.

Key words: insulin resistance, surrogate markers, atherosclerosis

CLC Number: