Basic & Clinical Medicine ›› 2018, Vol. 38 ›› Issue (10): 1452-1456.

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Research progress of paediatric Cushing’s disease


  • Received:2017-10-09 Revised:2017-12-01 Online:2018-10-05 Published:2018-09-28
  • Contact: Ren-zhi WANG,

Abstract: Paediatric Cushing’s disease, sharing the same etiology with that in adults, combines a series of clinical manifestations of hypercortisolism, attributed to the adrenal hyperplasia and hypercortisolemia caused by the excessive ACTH produced by pituitary ACTH adenoma or ACTH cell hyperplasia. Paediatric cushing’s disease has different clinical characteristics from that in adults with more complicated diagnostic procedures. Early diagnosis and treatment are very important for the prognosis of children patients.

Key words: cushing’s disease, diagnosis, treatment, progress

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