Abstract: Necroptosis plays crucial roles in the genesis and development of many diseases involved in different organisms and systems. Neuronal damage is common in all kinds of neurological diseases. According to recent reports, necroptosis is an important pattern of neuronal death. Inhibition of neuronal necroptosis shows protective roles in neurological diseases. Therefore, studies on neuronal necroptosis will be the focus of prevention and treatment of neurological diseases in the future.

Key words: cell death, necroptosis, nervous system