Basic & Clinical Medicine ›› 2014, Vol. 34 ›› Issue (12): 1710-1713.
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Abstract: Glucose regulated protein78,GRP78,called immunoglobulin binding protein, is a highly conserved stress protein which is produced by the organism in the stressor stimulation. GRP-78 protein appears to play a role in helping in the assembly of multimeric proteincomplexes in the endoplasmic reticulum (ER).The expression of GRP78/Bip plays a particularly vital role of dealing with the stress response in the liver which is important organ of the body metabolismand biochemical processing factory of various enzyme.
Key words: Glucose regulated protein78, liver, Heat Stress, Oxidative Stress, Endoplasmic Reticulum Stress
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2014/V34/I12/1710