Abstract: Objective To assess the clinical analgesic effect of transversus abdominis plane (TAP) block at transabdominal hysterectomy and myomectomy gynaecological surgeries. Methods Forty patients (ASA I/II) undergoing transabdominal hysterectomy or myomectomy gynaecological surgery were randomly divided into control group ( n=20) and TAP block group (n =20). Ultrasound-guided TAP block was practiced after general anesthesia induction, ropivacaine and normal saline were injected in TAP block group and control group separately. Intra-operative fentanyl consumption, post-operative rescue analgesic requirements, and post-operative NRS pain score were compared between the two groups. Results Intro-operative fentanyl consumption and post-operative rescue analgesic demand rate of TAP group were less than those of control group（P<0.05）. At the time of 4 hours after surgery, NRS pain score of TAP group was less than that of control group（P<0.05）. Conclusions TAP block can provide safe intro- and post-operative analgesia for transabdominal hysterectomy and myomectomy gynaecological surgeries.

Key words: TAP block, transabdominal hysterectomy, myomectomy, analgesia