Basic & Clinical Medicine ›› 2014, Vol. 34 ›› Issue (4): 509-513.

Previous Articles     Next Articles

Association between Metabolic Syndrome and Nonalcoholic Fatty Liver Disease in 6 660 physical examination population of Guilin


  • Received:2013-09-09 Revised:2013-11-20 Online:2014-04-05 Published:2014-03-31

Abstract: Objective To investigate association between metabolic syndrome(MS) and nonalcoholic fatty liver disease(NAFLD) in physical examination population of Guilin. Methods 6 660 persons were selected from medical center for health examination by cluster sampling method. The survey included questionnaire investigation, physical examination, metabolic characteristics and liver color doppler ultrasound examination, and body mass index(BMI) calculated. Results 1) Among the 6 660 participants, the prevalence of NAFLD、MS and (NAFLD+MS)were 19.1%、11.4% and 6.2%. The prevalence of NAFLD、MS and (NAFLD+MS) increased with age, the prevalence of age-stratified and gender-stratified were significant differences (P<0.01). 2) There were all significant differences of each component of MS in comparison of NAFLD and control group (P<0.01). 3) BMI、systolic blood pressure (SBP)、diastolic blood pressure (DBP)、fasting blood glucose(FPG)、triglyceride(TG)、total cholesterol(TC)、Low-density lipoprotein cholesterol(LDL-C)、alanine aminotransferase(ALT)、aspartate aminotransferase(AST) and uric acid(UA) in NAFLD group were significantly higher than in normal control group (P<0.01), high-density lipoprotein cholesterol(HDL-C) level was lower in NAFLD group than in normal control group (P<0.01). 4) Logistic regression anaIysis demonstrated that sex(male)、BMI、blood pressure、FPG、TG、LDL-C、ALT and UA were the risk factors of NAFLD, and HDL-C was the protective factor of NAFLD. Conclusions NAFLD was positively correlated with MS, and had the characteristics of each component of MS.

Key words: Nonalcoholic fatty liver disease, Metabolic syndrome, Relevance