Abstract: Abstract Dexmedetomidine is a novel and highly selectiveα2-adrenoceptor agonist. Dexmedetomidine offers beneficial pharmacological properties, providing dose-dependent sedation, analgesia, sympatholysis and without relevant respiratory depression. Resent studies of dexmedetomidine has proved that it can maintain hemodynamics during the perioperative period,decrease sympathetic tone,reduce the consumption of anaesthetic,prevent postanesthetic shivering and provide organ protection. This review aims to present the organ protection of dexmedetomidine.

Key words: Key words dexmedetomidine, α2-adrenoceptors, organ protection