Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (4): 695-699.doi: 10.16352/j.issn.1001-6325.2023.04.0695

• Mini Reviews • Previous Articles     Next Articles

Research progress on the role of adipokines in the pathogenesis of sarcopenia in the elderly

DANG Caihong1, LI Weixin2*   

  1. 1. the First School of Clinical Medicine, Lanzhou University, Lanzhou 730000;
    2. the Second Ward, Department of Geriatrics, the First Hospital of Lanzhou University, Lanzhou 730000, China
  • Received:2022-11-18 Revised:2023-02-15 Online:2023-04-05 Published:2023-04-03
  • Contact: *

Abstract: The change of fat distribution, the decrease of physical activity and the influence of diseases during aging will change the circulating level of adipokines. Adipokines may promote inflammation or anti-inflammation response, and keep glucose homeostasis and energy metabolism by regulating inflammatory reaction. Adipokines activate or inhibit the signal transduction pathway of substance metabolism, and play a role in the occurrence and development of muscle attenuation of aging organs. Paying attention to the role of adipokines in muscle attenuation will support the prevention and treatment of sarcopenia in the elderly.

Key words: adipokines, the elderly, sarcopenia

CLC Number: