Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (1): 179-183.

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Research progress of circular RNAs in prostate cancer


  • Received:2020-09-07 Revised:2021-05-24 Online:2022-01-05 Published:2022-01-05

Abstract: Circular RNAs (circRNAs) are non-coding RNAs with unique covalently closed circular structures, which are widely found in eukaryotic cells. Recent studies have shown that circRNAs are involved in the pathophysiological processes of various diseases, including malignant tumors, by regulating microRNAs, binding to proteins, and regulating transcription and splicing processes. The special structure and complex functions of circRNAs make them have great research potential in the field of cancer. Prostate cancer is one of the most common malignancies among men in the world. At present, the pathogenesis and treatment of prostate cancer still need to be further studied.

Key words: circular RNA, prostate cancer, gene regulation

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