Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (1): 145-148.
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Abstract: Schwann cells (SCs) have strong plasticity. After peripheral nerve injury, Schwann cells dedifferentiate into repair phenotype and dominate the repair process. C-Jun N-terminal kinase, mitogen activated protein kinase and other signaling pathways and transcriptional regulators are involved in regulating Schwann cell-mediated repair process. In this review, we discuss the main signaling pathways and transcriptional regulators of Schwann cell promoting peripheral nerve regeneration.
Key words: peripheral nerve, Schwann cells, signal pathway, nerve regeneration, repair mechanism
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URL: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/
http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2022/V42/I1/145