Research progress on the role of epigenetic regulation in obstructive sleep apnea syndrome

Abstract

Abstract: Chronic intermittent hypoxia plays an important role in the mechanism of various adverse reactions of obstructive sleep apnea syndrome (OSA). Epigenetic process participates in the occurrence and development of OSA and complications by affecting adaptive potential and phenotypic variation under chronic intermittent hypoxia. Therefore, understanding the effect of epigenetic regulation on OSA is helpful to provide new ideas for clinical phenotype and targeted therapy of OSA.

Key words: obstructive sleep apnea, epigenetic, DNA methylation, histone modification, non-coding RNA

CLC Number:

Q39
R563.9

CHEN Feng, LENG Yu-fang, REN Yi-xing, ZHANG Jian-min, LIU Xin, SHI Ya-jing. Research progress on the role of epigenetic regulation in obstructive sleep apnea syndrome[J]. Basic & Clinical Medicine, 2021, 41(6): 899-903.

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