Basic & Clinical Medicine ›› 2021, Vol. 41 ›› Issue (2): 262-266.

• Mini Reviews • Previous Articles     Next Articles

Regulatory effects and mechanisms of HOTAIRM1 in malignant tumors

ZHAO Yu-qiao, SU Zhi-lei, CUI Yun-fu, GUAN Cang-hai, JIANG Xing-ming*   

  1. Department of HPB Surgery, the 2nd Affiliated Hospital of Harbin Medical University, Harbin 150086, China
  • Received:2020-02-17 Revised:2020-04-26 Online:2021-02-05 Published:2021-01-19
  • Contact: *

Abstract: HOTAIRM1, a newly found long non-coding RNA (lncRNA), is abnormally expressed in diverse malignant tumors, regulated mRNA, miRNA, relevant target gene or protein through specific signal transduction pathways to function in mechanisms of proliferation, invasion and metastasis of tumor cells. HOTAIRM1 is closely related to the clinicopathology or molecular pathology and have shown great potential in therapy and predicting prognosis of patients.

Key words: long non-coding RNA, HOTAIRM1, tumors, regulatory effects

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