Basic & Clinical Medicine ›› 2021, Vol. 41 ›› Issue (1): 112-115.

• Mini Reviews • Previous Articles     Next Articles

Research progress of thrombus compositions and imaging manifestations in patients with acute ischemic stroke

LIU Jia-yi1, ZHANG Zheng-xiang2*, YAN Min-li2, QI Guan-shu2, CHEN Qiang2, HOU Qun2   

  1. 1. the First School of Clinical Medicine, Zhejiang Chinese Medical University, Hangzhou 310053;
    2. Department of Neurology, the First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Traditional Chinese Medicine), Hangzhou 310006, China
  • Received:2020-06-03 Revised:2020-10-13 Online:2021-01-05 Published:2020-12-30
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Abstract: With the rapid development of intravascular interventional treatment, the study of thrombus in patients with acute ischemic stroke (AIS) has been intensified in recent vears. The composition of thrombus mainly includes red blood cells, fibrin/platelets, white blood cells, and von Willebrand factor (vWF) and other rare components, which can be manifested as arterial hyperdensity sign (HAS) and susceptibility vessel sign (SVS) on non-contrast CT(NCCT) and magnetic resonance imaging (MRI). Further analysis of thrombus components and imaging manifestations will help to understand the etiology, treatment selection and clinical prognosis of AIS.

Key words: thrombus compositions, white blood cells, von willebrand factor(vWF), hyperdense artery sign(HAS), susceptibility vessel sign(SVS)

CLC Number: