Basic & Clinical Medicine ›› 2020, Vol. 40 ›› Issue (8): 1103-1108.

• Mini Reviews • Previous Articles     Next Articles

Application of new orally anticoagulants in patients with chronic kidney disease

WANG Xiu-heng3, WU Jie2, HU Heng-jing1,2*   

  1. 1. Postdoctoral Research Station of Basic Medicine, University of South China;
    2. Department of Cardiology Lab, the First Affiliated Hospital of University of South China;
    3. Department of Nuclear Medicine Lab, the First Affiliated Hospital of University of South China, Hengyang 421000, China
  • Received:2019-07-04 Revised:2019-12-06 Online:2020-08-05 Published:2020-07-29
  • Contact: *bestmanhhj@hotmail.com

Abstract: Novel oral anticoagulants (NOVACs) as blood coagulation factor inhibitors have exhibited pivotal role in thromboembolic event and ischemic cardiovascular disease. Nevertheless, it's application in chronic kidney disease (CKD) patients of stage 3-5 remains controversial. This paper reviewed currently recommended usage of NOACs in CKD patients of stage 3-5 in the evaluation of anticoagulation related nephropathy, clinical monitoring and assessment of NOACs.

Key words: chronic kidney disease, new oral anticoagulant, embolization

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