Abstract: Massive open online course has become a hot issue about researching and discussion nowadays. This is a big challenge for the traditional teaching, with its characteristics of large-scale, openness and curriculum miniaturization. Massive open online course initiates a revolution in medical curriculum learning, depending on the advantages of flexible teaching time, freedom of learning time, rich curriculum resources, fair and reasonable evaluation system. Under the new educational mode, human anatomy as an important medical basic course needs to use the superiority of massive open online courseto improve the teaching effect, with the help of optimizing the curriculum content, changing teaching mode and innovating the evaluation system.

Key words: Key words: massive open online course, human anatomy, teaching reform