Research progress on gene mutations and targeted therapy of type II endometrial carcinoma

Basic & Clinical Medicine ›› 2019, Vol. 39 ›› Issue (2): 277-280.

Research progress on gene mutations and targeted therapy of type II endometrial carcinoma

Hai-Fang WUXiang-Yu MENG²,Heng-Yi Xu², ²

Received:2017-11-23 Revised:2018-01-24 Online:2019-02-05 Published:2019-01-16

Abstract: Endometrial carcinoma (EC) is one of the most commen gynecological cancer, Its subtype non-estrogen-dependent endometrial carcinoma (type II) is usually associated with gene abnormalities such as P53 gene mutation and HER-2 overexpression. Molecular targeted therapy may improve the therapeutic effect and prognosis of type II endometrial carcinoma.

Key words: Type II endometrial carcinoma, Gene mutation, Targeted therapy

Cite this article

Hai-Fang WU Xiang-Yu MENG Heng-Yi Xu. Research progress on gene mutations and targeted therapy of type II endometrial carcinoma[J]. Basic & Clinical Medicine, 2019, 39(2): 277-280.

share this article

/ Recommend

Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks

URL: https://journal11.magtechjournal.com/Jwk_jcyxylc/EN/

https://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2019/V39/I2/277

References

Related Articles 15

[1]	GAO Yidan, JIANG Xuehan, ZHANG Hong, YANG Peiran. Development of novel therapies targeting at dysregulated signaling pathways in pulmonary arterial hypertension [J]. Basic & Clinical Medicine, 2024, 44(8): 1088-1093.
[2]	DUAN Ran, LI Qingyuan, FENG Tong. Metabolic reprogramming in idiopathic pulmonary fibrosis [J]. Basic & Clinical Medicine, 2024, 44(6): 882-886.
[3]	. Drug therapy for intracranial germ cell tumor [J]. Basic & Clinical Medicine, 2024, 44(10): 1350-1356.
[4]	. Advances in pharmacotherapy for angiosarcoma [J]. Basic & Clinical Medicine, 2024, 44(10): 1363-1367.
[5]	. Targeted therapy and immunotherapy for malignant mesothelioma [J]. Basic & Clinical Medicine, 2024, 44(10): 1342-1349.
[6]	LIU Jingwen, SONG Haoxin, ZHU Lei. Construction and drug resistance evaluation of cell strains which stably express FIP1L1-PDGFRA protein and its mutants [J]. Basic & Clinical Medicine, 2024, 44(1): 63-68.
[7]	GONG Ziqi, WU Xiaowen, GUO Qian, GUO Jun, KONG Yan. Influence of PTEN mutation on pathological features and prognosis of patients with mucosal melanoma [J]. Basic & Clinical Medicine, 2023, 43(9): 1341-1345.
[8]	HE Dan, RUAN Zhong-bao. Extracellular vesicles in the pathogenesis of atrial fibrillation [J]. Basic & Clinical Medicine, 2022, 42(4): 671-674.
[9]	LYU Xue, LI Xue-wei, YANG Ting, ZHENG Jin-xiu, ZHU Zi-he, YANG Tao, XU Jun. Bioinformatic analysis of adenocarcinoma at esophagogastric junction and mutation sites screening of Involucrin gene [J]. Basic & Clinical Medicine, 2022, 42(2): 235-242.
[10]	TENG Cong-cong, XU Yong-mei, TANG Shu-ping, LI Yong, YANG Yang, LONG Lan, ZHANG Jie. Epidemiological investigation of thalassemia in gestational age population of Dai nationality in Dehong Prefecture, Yunnan Province [J]. Basic & Clinical Medicine, 2022, 42(10): 1504-1508.
[11]	WANG Zhi-xin, ZUO Qing-yao, LI Wei, CHEN Jia, DENG Wei. Molecular genetic analysis and clinical consideration of two families with GCK gene mutation [J]. Basic & Clinical Medicine, 2020, 40(12): 1640-1644.
[12]	. Research progress of circular RNA in tumors [J]. Basic & Clinical Medicine, 2019, 39(3): 409-413.
[13]	. Analysis of clinical and gene mutation characteristics in four patients with short chain acyl-CoA dehydrogenase deficiency [J]. , 2019, 39(11): 1574-1577.
[14]	. Rare mutation of angiopoietin-like protein 8 gene and severe hypertriglyceridemia [J]. Basic & Clinical Medicine, 2018, 38(5): 622-625.
[15]	. Mutations of P16INK4a/CDK4/CCND1 genes in 134 Chinese melanoma patients and their clinical significance [J]. Basic & Clinical Medicine, 2018, 38(2): 153-157.

Metrics

Viewed

Full text

Abstract

Comments

Abstract
References
Related Articles
Recommended Articles
Metrics
Comments

TOP