Abstract: Objective To explore the effect of multiple disciplinary team(MDT) combined with problem-based learning (PBL) in clinical practice teaching of neurology. Methods a total of 72 5-year medical students majoring in clinical medicine in grade 2014 of Xiangya Second Hospital of Central Couth University, who had clinical practice in neurology from June 2018 to December 2018, were randomly divided into the experimental group (MDT-PBL group) and the control group (LBL group) to compare the exam results and questionnaire survey results of the two groups. Results the MDT-PBL group's theoretical test score (86.65±4.03) was significantly higher than that of LBL group (81.77±3.77) (P < 0.001). The score of clinical skills operation test in MDT-PBL group (87.42±3.71) was also significantly higher than that in LBL group (78.23±4.84) (P < 0.001）. The teaching satisfaction of MDT-PBL group was significantly better than that of the LBL group (P < 0.001）. Conclusion MDT combined with PBL teaching mode has achieved good results in clinical practice teaching of neurology, which is worthy of further promotion in clinic teaching.

Key words: multiple disciplinary team(MDT), problem-based learning (PBL), clinical practice, neurology