Abstract: Sterol regulatory element-binding proteins (SREBPs), as a major regulator of liposome in vivo, plays an important role in controlling liver lipid synthesis and inducing expression of genes involved in fatty acid, triglyceride and cholesterol synthesis. Part of the traditional Chinese medicine and its derivatives can be through the SREBP target treatment of lipid metabolism related diseases.

Key words: sterol regulatory element-binding proteins（SREBPs）, lipid metabolism, pharmacology of traditional chinese medicine