Basic & Clinical Medicine ›› 2017, Vol. 37 ›› Issue (11): 1634-1639.

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Progress in the research of acquired heterotopic ossification


  • Received:2017-04-27 Revised:2017-09-15 Online:2017-11-05 Published:2017-11-01
  • Supported by:
    Injury induced,BMP dependent heterotopic osteogenic MSC niche as mechanism of heterotopic ossification

Abstract: Acquired heterotopic ossification is the abnormal bone formation outside of the normal skeletal system .The origin trauma and disease of aHO is plentiful. In this review, we focus on BMP,hedgehog,wnt/β-catenin and NF-κB signaling pathway, understanding of the pathogenesis of aHO.

Key words: acquired heterotopic ossification , signaling pathway, pathogenesis

CLC Number: