Basic & Clinical Medicine ›› 2016, Vol. 36 ›› Issue (2): 258-261.
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Abstract: Neuropilin-1(NRP1) is an important member of the NRP-family, which plays an important role in neural development, angiogenesis, tumor metastasis and immunity as NRP1 in various fields. NRP1 can promote tumor angiogenesis, proliferation and metastasis through a variety of mechanisms, while in the immune system it can regulate the primary immune response and which is a key factor in anti-tumor immunity. Further research of NRP1 will provide new directions and opportunities for the nervous system, vascular system and tumor treatment.
Key words: neuropilin-1(NRP1), angiogenesis, malignancies, immunity
CLC Number:
R730.5
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2016/V36/I2/258