Basic & Clinical Medicine ›› 2015, Vol. 35 ›› Issue (6): 830-832.
Previous Articles Next Articles
Received:
Revised:
Online:
Published:
Abstract: Objective: To study the clinical characteristics of pure androgen-producing adrenal adenoma. Method: Clinical data from 7 cases with pure androgen-producing adrenal adenoma treated in PUMCH from 2002 to 2014 were analyzed retrospectively. Results:Seven patients with age at onset from 3.5 to 31 years had various clinical courses from 1.5 to 30 years. All female patients (n=6) had virilism and one male patient developed sexual precocity. Serum testosterone levels were 4.1-33.0 nmol/L preoperatively and in the females decreased to 0.1-1.3nmol/L postoperatively accompanying with relief of the symptoms, and decreased to 4.1mmol/L for the boy because of secondary central precocious puberty. All the tumors were histologically diagnosed with adrenocortical adenoma. Conclusions: Pure androgen-producing adrenal adenoma usually occurs in childhood. Clinical characteristics are various according to the sex and age of the patients. Androgen-producing adrenal adenoma should be suspected when the patients develop virilism, menstrual disorder, or sexual precocity.
Key words: Adrenal adenoma, Hyperandrogenemia, Clinical characteristics, Treatment
CLC Number:
R586.9
0 / / Recommend
Add to citation manager EndNote|Reference Manager|ProCite|BibTeX|RefWorks
URL: http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/
http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2015/V35/I6/830