Basic & Clinical Medicine ›› 2015, Vol. 35 ›› Issue (3): 417-420.
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Abstract: Leukaemia stem cells (LSCs) is the main source of drug resistance, recur- rence and poor prognosis in treatment of chronic myeloid leukemia (CML). Specific elimination of LSCs is expected to become a way to cure CML. The signaling path-ways in LSCs are abnormal, such as WNT/β –catenin,JAK/STAT,PI3K/AKT, and so on.
Key words: chronic myeloid leukaemia, leukaemia stem cells, signaling pathway
CLC Number:
R733.7
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2015/V35/I3/417