Basic & Clinical Medicine ›› 2015, Vol. 35 ›› Issue (2): 257-261.
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Abstract: MicroRNAs (MiRNAs) is one kind of highly conservative endogenous non-coding single-stranded RNAs with small molecule, it is able to regulate gene expression at the translation level by non-specific identification of target genes’ mRNA, and it can regulate various biological functions of cells. Up to now a variety of microRNAs have been found, in which MiR-126 mainly exists in vascular endothelial cells and platelets, and is closely related to the generation, development and repairing of blood vessels. Therefore, MiR-126 will become a very good breach to study coronary heart disease and other vascular diseases.
Key words: miR-126, blood vessel, VEGF, VCAM-1
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2015/V35/I2/257