Abstract: Microparticles, a kinds of small vesicles derived from the mother cells with a variety of contents, have been reported to involve in a variety of pathophysiological processes. The variety of contents which microparticles contain also can affect the coagulation function and inflammation.. And microparticles can also influence the apoptosis of endothelial cells and the function of vascular barrier through various mechanisms. Therefore, microparticles have great significance on the occurrence and progress of acute lung injury.

Key words: microparticles, acute lung injury, inflammation