Basic & Clinical Medicine ›› 2014, Vol. 34 ›› Issue (3): 406-409.

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Progress in the study of epigenetic regulation in osteoporosis


  • Received:2013-03-18 Revised:2013-05-07 Online:2014-03-05 Published:2014-02-27

Abstract: Epigenetics are such heritable modifications as DNA methylation, histone modification, chromatin remodeling, as well as miRNA, without changes in DNA sequence. It has been shown that occurence of osteoporosis is closely related to the interactions between the genome and enviroment, in which epigenetic regulation play an important role.

Key words: Epigenetics, Osteoporosis, DNA methylation, Histone modification, miRNA

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