Basic & Clinical Medicine ›› 2013, Vol. 33 ›› Issue (5): 627-630.
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Abstract: The axon guidance molecule Slit3 is a secreted extracellular matrix protein that was found in recent years. Genetic function studies revealed that Slit3 is dispensable for neural development but required for non-neuron-related developmental. Recent study suggests that Slit3 is a new angiogenic factor implicated in regulating a variety of life activities, such as cell migration, angiogenesis, organogenesis, reproductive regulation, tumourigenesis and mental disease.
Key words: axon guidance molecule, Slit3, cell migration, angiogenesis, organogenesis
CLC Number:
R331.32
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2013/V33/I5/627