Abstract: Objective To investigate the clinical features and treatment strategy for primary SRCC of the bladder. Methods 1 case of primary bladder SRCC was studied，inc1uding clinica1 features，treatment，and review the status of the disease along with the literature. Results The case received ultrasound，CT ,biopsy and other related lab tests for diagnosis and differential diagnosis．Laparoscopic radica1 cystectomy and orthotopic ileal neobladders were performed．Chemotherapy was delivered after surgery. Conclusion Primary SRCC of the bladder lacks distinctive clinica1 and imaging manifestations, with high malignancy and relatively poor prognosis . Radica1 cystectomy and chemotherapy is one of the optimal approaches for the treatment of SRCC of bladder.

Key words: bladder neoplasms, signet ring cell carcinoma, diagnosis, treatment