Abstract: Ischemia/hypoxia is one of the common pathophysiological processes in many clinic diseases. The stabilities and diverse functions of miRNA-210 in ischemic / hypoxic state have been caused widespread concern. This article analyzes the effects of miRNA-210 on mitochondrial metabolism and angiogenesis in the ischemic / hypoxic state; then, attention is focus on the roles of miRNA-210 in ischemic / hypoxic diseases, such as myocardial infarction, stroke and cancer.

Key words: [Keywords] miRNA-210, ischemic/hypoxic injuries, cancer, mitochondria metabolism, angiogenesis