Basic & Clinical Medicine ›› 2013, Vol. 33 ›› Issue (10): 1341-1344.
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Abstract: Reactive oxygen species ( ROS ) are byproduct of vivo aerobic cells in the metabolic process , including O2 - 、H2O2 、 ? OH and HO2- . Existing studies have shown that when the balance of ROS generation and clear broken , then ROS through damage mitochondria 、activate the death receptor , affect the expression of cytokines and activate the transcription factor , to participate and influence the cell signal transduction mechanisms , which has a crucial regulatory for the cell apoptosis and proliferation.
Key words: ROS, Cell apoptosis, Proliferation
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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2013/V33/I10/1341