Basic & Clinical Medicine ›› 2012, Vol. 32 ›› Issue (12): 1477-1480.

Previous Articles     Next Articles

Immunological applications of phage display peptide library

  

  1. 1.
    2. Xinjiang Medical University
  • Received:2011-11-18 Revised:2012-05-13 Online:2012-12-05 Published:2012-11-28

Abstract: Phage display libraries of peptides has proven to be a powerful technology for selecting polypeptides with desired biological and physicochemical properties from huge molecular libraries. Fragments of foreign peptides or proteins are expressed as fusion proteins displayed on the phage surface, which keep their relatively independent spatial structure and biological activity. This technique has unique advantages and great potentials in the many fields such as research of protein interaction and developments of antibodies,vaccine and drugs.

Key words: Key Word: phage display library, epitope, vaccine