Abstract: Objective To investigate the clinical features and treatment methods of ectopic pancreas. Methods Retrospective analysis of 32 pathologically confirmed patients with ectopic pancreas in Peking Union Medical College Hospital from 1992 to 2010. Results Thirty-two cases with heterotopic pancreas located in the stomach（15 cases）, duodenum（4 cases）, jejunum（9 cases） and ileum（4 cases）, and 26 cases were detected in recent 4 years. Eight cases were diagnosed before surgery, 6 cases were misdiagnosed as gastrointestinal stromal tumors, 5 cases were misdiagnosed as leiomyoma, 1 case was misdiagnosed as malignant gastric ulcer; the remaining 12 cases were found accidentally in other abdominal surgery. One case was confirmed by routine endoscopic biopsy，the rest 31 cases accepted surgical resection and confirmed by postoperative pathologic findings; all patients had no complications. Conclusions Gastrointestinal submucosal protuberant lesions should be considered the possibility of ectopic pancreas, endoscopic procedure or surgical resection are available if confirmed diagnosis is made.

Key words: heterotopic pancreas, diagnosis, treatment