Angiotensin-converting enzyme 2 as a new therapeutic target for cardiovascular fibrosis

Abstract

Abstract: Angiotensin-converting enzyme 2 (ACE2) is the first human homologue of ACE, being a new therapeutic target for cardiovascular fibrosis and remodeling. This review focuses on the biological features of ACE2, ACE2 and its modulation in cardiovascular fibrosis as well as the latest advance in prevention and treatment of cardiovascular fibrosis.

Key words: angiotensin-converting enzyme 2, cardiovascular fibrosis, angiotensin II, remodeling

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Wei WU; Jiu-chang ZHONG; Jun-ming GUO. Angiotensin-converting enzyme 2 as a new therapeutic target for cardiovascular fibrosis[J]. Basic & Clinical Medicine, 2010, 30(7): 778-781.

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http://journal11.magtechjournal.com/Jwk_jcyxylc/EN/Y2010/V30/I7/778

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