Programmed death receptor 1 and viral hepatitis C

Basic & Clinical Medicine ›› 2010, Vol. 30 ›› Issue (11): 1218-1221.

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Programmed death receptor 1 and viral hepatitis C

Jun-ying ZHOU, Feng WEI, Jun-qing LI

Dept of Infection, the Third Hospital; Hebei Medical University

Received:2009-12-17 Revised:2010-03-01 Online:2010-11-05 Published:2010-11-05
Contact: Jun-ying ZHOU,

Abstract

Abstract: Programmed death 1 (PD-1) can exhaust the function of virus-specific CD8+ T cells PD-1 increased in the chronic progress of HCV infection. Blockage of PD-1 signal pathway may restore the immunological function of CD8+ T cell, which benefit for virus clearance.

Key words: programmed death 1, viral hepatitis C, regulatory T cells, programmed death 1, viral hepatitis C, regulatory T cells

Jun-ying ZHOU; Feng WEI; Jun-qing LI. Programmed death receptor 1 and viral hepatitis C[J]. Basic & Clinical Medicine, 2010, 30(11): 1218-1221.

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Programmed death receptor 1 and viral hepatitis C

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