Abstract: Objective To observe the effects of Shenhong (SH) combined with chemotherapeutic drugs on curative effect, symptoms improvement, and immunology function in 393 metaphase or terminal cancer patients. Methods All 598 patients were divided into two groups. One was the control group that had 205 patients treated with chemotherapeutic drugs. The other one was SH-treated group, which had 393 patients treated with SH combined with chemotherapeutic drugs that were given for 60 days. Then, the data were recorded and analyzed for all cases. Results Compared with control patients, the total remission was 42.0% in SH-treated patients. The improvement rates of pain, cough, debilitation, and anepithymia were 71.9%. The Karnofsky grade was increased by 27.0%. Besides, the CD3+ and CD4+ were increased by 11.6% and 19.3%, but CD8+ was decreased by 22.6% at the same time. The patients CD4+/ CD8+ was enhanced by 54.2%, while the NK cell activity and marophage phagocysis were improved significantly. It was also seen that the content of Ig G and Ig A were increased in the same group. Conclusion It is clear that the curative effect of SH combined with chemotherapeutic drugs were higher than that of chemotherapeutic drugs in the metaphase or terminal cancer patients. The therapeutic effect of SH is regarded as the immunology regulation.

Key words: Shenhong capsule(SH), chemotherapeutic drugs, curative effect, Karnofsky grade, immunology