Abstract: The present research discussed the influence of Noradrenergic systems in Lateral Hypothalamus Area (LHA) on small intestine moving and possible operating mechanism.. Methods: The effect of injecting different drugs including saline、 noradrenalin、noradrenalin+phentolamine、noradrenalin+propolol、phentolamine on small intestines electro-activity of rats was detected by external alimentary canal electrodes, and by the central nervous system stereo-configuration technology, in which the Migrating Myoelectric Complex (MMC) indexes as the cyclic period, the ratio of the active time to the cyclic period, and the number of the fast wave within the active time per minute were used..Results: For LHA, the cyclic period of MMC extended, the ratio of the active time to the cyclic period and the number of the fast wave within the active time per minute reduced, after injecting 4mg/2ml Noradrenaline (NE). These results were considerably different with the saline group. NE inhibited the electro-activity of small intestine of rats, and the average effective time was 36.86+7.39 min. This function was retarded by injecting 10mg/2ml phentolamine into LHA, rather than the same dose of propolol. Hence injecting 10mg/2ml PE alone to LHA raised the ratio of the MMC active time to the cyclic period, which obviously appeared a disagreement compared with the saline group. And phentolamine presented a slight excitability on the electro-activity of small intestine of rats. Conclusion: The NE in LHA showed the inhibitive regulation effect on small intestines, and this effect was introduced through a acceptor and might be irrelevant to b acceptor. The a acceptor in LHA involved in the inhibition of the electro-activity in small intestines.