Basic & Clinical Medicine ›› 2007, Vol. 27 ›› Issue (2): 152-156.

• 研究论文 • Previous Articles     Next Articles

Analyze the indices of the screeing test of hyperlipidemia by logistie regression analysis and ROC study in chilren

  

  • Received:2006-04-10 Revised:2006-10-23 Online:2007-02-25 Published:2007-02-25

Abstract: Objective The present study was designed to examine the serum lipid levels, investigate the risk factors of dyslipidemia in children and study the indices of screening test for dyslipidemia of children in Beijing. Methods Serum total cholesterol (TC), triglyceride (TG), high density lipoprotein-cholesterol (HDL-c) and low density lipoprotein-cholesterol (LDL-c) were detected by HITACHI 7060 automatic biochemical analyzer in Beijing students. Body height, weight, upper body height, waist circumference, upper arm circumference and blood pressure were measured. Body mass index (BMI) was calculated according to the measurement of body height and weight. Waist-to-height ratio (WHR) was also calculated. Then a Logistic regression analysis and ROC study were conducted to examine the relationship between the above indices and dyslipidemia. Results Of 962 students, 107 were found dyslipidemia. The prevalence rate was 11.12%. The upper body height, upper arm circumference, BMI, WHR, systolic pressure and diastolic pressure in children with dyslipidemia were higher than those of normal subjects (P<0.05). BMI, WHR, diastolic pressure and positive familial history were risk factors of children dyslipidemia. Conclusion High risk group of dyslipidemia in children should be screened by BMI, WHR, pressure and familial history. And further fasting plasma lipid concentrations should be detected.