Basic & Clinical Medicine ›› 2023, Vol. 43 ›› Issue (2): 341-345.doi: 10.16352/j.issn.1001-6325.2023.02.341

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Role of neutrophils in the development and progression of COVID-19

WANG Liang, SI Ping, SHEN Yongming, CUI Xiaoming*   

  1. Department of Clinical Laboratory, Tianjin Children's Hospital/Children's Hospital of Tianjin University,Tianjin 300074, China
  • Received:2021-12-30 Revised:2022-04-07 Online:2023-02-05 Published:2023-02-02
  • Contact: *

Abstract: Neutrophils are more innate immune cells found in coronavirus disease in 2019(COVID-19). The accounting of neutrophils and the level of plasma neutrophil extracellular traps(NETs) were positively correlated with the severity of COVID-19. This article reviews the relevant studies of neutrophils, formation and degradation of NETs involved in the pathological process of COVID-19, providing the reference for further studies of pathogenesis and intervention.

Key words: COVID-19, SARS-CoV-2, neutrophil, neutrophil extracellular traps

CLC Number: