Basic & Clinical Medicine ›› 2022, Vol. 42 ›› Issue (4): 646-650.doi: 10.16352/j.issn.1001-6325.2022.04.018

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Research progress on assessment of serum biomarkers related to senile frailty

DAI Jing-rong1,2, LI Jie1,2, HE Xu1,2, LI Yan1,2*   

  1. 1. School of Medicine, Kunming University of Science and Technology,Kunming 650500;
    2. Department of Geriatrics, the First People's Hospital of Yunnan Province, Kunming 650032,China
  • Received:2021-07-28 Revised:2021-11-11 Online:2022-04-05 Published:2022-04-01
  • Contact: *

Abstract: The assessment of senile frailty still implemented with scales and questionnaires. This subjective assessment method is prone to vary greatly with the assessors and scales. Therefore, it is particularly important to explore the Objective diagnosis basis of frailty.With the continuous development of population cohort and observational studies, great progress has been made in the serology of senile frailty.This article mainly reviews the influence mechanism of serum inflammatory factors, hormones, vitamins, homocysteine and related protein molecules on frailty and provides new ideas to further exploring the Objective diagnosis basis of frailty in the elderly.

Key words: frailty, biological markers, mechanism, aged

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